BGC > Product Search > 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylic acid | 1078166-57-0

Molecular Formula: C22H21F3N6O3S
Molecular Weight: 506.5007496
WGKGermany: 3

Molecular Formula: C22H21F3N6O3S
Molecular Weight: 506.5007496
WGKGermany: 3

Description :
PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea.

• Molecular Weight :409.41
• Purity :98%

Molecular Formula :
C23H20FNO5
Canonical SMILES :
COC1=CC2=C(C=C1)C=C(C=C2)OCC3(CN(C3)C(=O)C4=CC=C(C=C4)F)C(=O)O
InChI :
InChI=1S/C23H20FNO5/c1-29-19-8-4-17-11-20(9-5-16(17)10-19)30-14-23(22(27)28)12-25(13-23)21(26)15-2-6-18(24)7-3-15/h2-11H,12-14H2,1H3,(H,27,28)
InChIKey :
LWJGMYMNSNVCEM-UHFFFAOYSA-N
Solubility :
DMSO: 81mg/mL(197.84mM); Water: <1mg/mL(<1mM); Ethanol: <1mg/mL(<1mM)
Appearance :
White Solid
Storage : 3 years -20℃ powder; 6 months -80℃ in solvent
Synonyms :
PF04418948; PF-04418948; PF 04418948; PF4418948; PF-4418948; PF 4418948.

More details are to be found here

Smile code:
O=C(C1(COC2=CC=C3C=C(OC)C=CC3=C2)CN(C(C4=CC=C(F)C=C4)=O)C1)O
MDL Number:
MFCD24387541
Purity :
98+%
Available in stock:
12.783 g

More details are to be found here